Template Industrial Report

Nah epul dan rakan2 yg lain,aku dah masukkan kt sini.

Results

Practical 1: Granulation

Weight of binder used: g??

Weight of empty container = g

Weight of container + wet granules = X

Weight of container + dry granules = X2

Weight of wet granules = X – g = Y

Weight of dry granules = X2 – g = Y2

% Loss on drying (LOD)

= Weight of water in sample x 100

Total of wet sample

= Y-Y2 x 100

Y

= %

Weight of glidant (Magnesium Stearate) used:

1 x Z = Z2

100

Z= berat yg last skali lepas sume benda dh amik

Table of weight of binder used and % lost of drying

Groups	Weight of binder used (g)	% loss of drying, LOD (%)
A (4% HPMC)
B (6% HPMC)
C (8% HPMC)
D (4% starch)
E (6% starch)
F (8% starch)
G (10% starch)

Practical 2: Tabletting

Angle of Repose for group D (4% starch)

	First reading (g)	Second reading (g)	Third reading (g)	Average (g)
Granules without glidant
Granules with glidant
PCM powder

Bulk density = M

100ml

= M2 g/ml

Tapped density = Ng

88ml

= N2 g/ml

Carr’s Index = Tapped density – bulk density x 100

Tapped density

= N2 – M2 x 100

N2

= %

Table of average angle of repose

Groups	Angle of repose
	Granules without glidant	Granules with glidant	PCM powder
A (4% HPMC)
B (6% HPMC)
C (8% HPMC)
D (4% starch)
E (6% starch)
F (8% starch)
G (10% starch)

Table of Carr’s index value for every group

Groups	Density (g/ml)		Carr’s index (%)
	Bulk	Tapped
A (4% HPMC)
B (6% HPMC)
C (8% HPMC)
D (4% starch)
E (6% starch)
F (8% starch)
G (10% starch)

Granules size distribution for group ??

Amount granules poured in the shaker = g??

Sieve	Weight of granules (g)	Percentage granule size distribution (%)
1mm
500μm
250μm
125μm
Powder (<>
Total

Table of the highest percentage of granules size distribution

Groups	The highest percentage of granule size distribution (%)	The size of sieve of the highest percentage of granule size distribution (μm)
A (4% HPMC)
B (6% HPMC)
C (8% HPMC)
D (4% starch)
E (6% starch)
F (8% starch)
G (10% starch)

Practical 3: Quality control test

Table weight uniformity and tablet hardness for group ??

No.	Thickness (mm)	Diameter (mm)	Hardness (N)	Weight (g)
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
Average

Table of average thickness, diameter, hardness and weight

Groups	Average Thickness (mm)	Average Diameter (mm)	Average Hardness (N)	Average Weight (g)
A (4% HPMC)
B (6% HPMC)
C (8% HPMC)
D (4% starch)
E (6% starch)
F (8% starch)
G (10% starch)

riability Test

Weight of 20 tablets (before test) = Kg

Weight of 20 tablets (after test) = K2 g

% lost powder = K-K2 x 100

K

= %

Table of percentage lost of powder

Groups	Weight of 20 tablets (g)		Percentage lost powder (%)
	Before	After
A (4% HPMC)
B (6% HPMC)
C (8% HPMC)
D (4% starch)
E (6% starch)
F (8% starch)
G (10% starch)